diff --git a/js/xpconnect/src/XPCWrappedNative.cpp b/js/xpconnect/src/XPCWrappedNative.cpp
--- js/xpconnect/src/XPCWrappedNative.cpp
+++ js/xpconnect/src/XPCWrappedNative.cpp
@@ -1152,16 +1152,20 @@ bool XPCWrappedNative::CallMethod(XPCCal
   if (NS_FAILED(rv)) {
     return Throw(rv, ccx);
   }
 
   JS::Rooted<CallMethodHelper> helper(ccx, /* init = */ ccx);
   return helper.get().Call();
 }
 
+#if (__GNUC__ && __linux__ && __PPC64__ && _LITTLE_ENDIAN)
+// Work around a compiler bug on ppc64le (bug 1512162).
+__attribute__ ((noinline,noclone))
+#endif
 bool CallMethodHelper::Call() {
   mCallContext.SetRetVal(JS::UndefinedValue());
 
   mCallContext.GetContext()->SetPendingException(nullptr);
 
   if (mVTableIndex == 0) {
     return QueryInterfaceFastPath();
   }
@@ -1310,16 +1314,20 @@ bool CallMethodHelper::GetOutParamSource
         return false;
       }
     }
   }
 
   return true;
 }
 
+#if (__GNUC__ && __linux__ && __PPC64__ && _LITTLE_ENDIAN)
+// Work around a compiler bug on ppc64le (bug 1512162).
+__attribute__ ((noinline,noclone))
+#endif
 bool CallMethodHelper::GatherAndConvertResults() {
   // now we iterate through the native params to gather and convert results
   uint8_t paramCount = mMethodInfo->GetParamCount();
   for (uint8_t i = 0; i < paramCount; i++) {
     const nsXPTParamInfo& paramInfo = mMethodInfo->GetParam(i);
     if (!paramInfo.IsOut()) {
       continue;
     }