diff --git a/srcpkgs/python3-grpcio/template b/srcpkgs/python3-grpcio/template
new file mode 100644
index 0000000000..10bb03582a
--- /dev/null
+++ b/srcpkgs/python3-grpcio/template
@@ -0,0 +1,50 @@
+# Template file for 'python3-grpcio'
+pkgname=python3-grpcio
+version=1.32.0
+revision=1
+wrksrc="${pkgname#*-}-${version}"
+build_style=python3-module
+hostmakedepends="python3-setuptools python3-six"
+makedepends="python3-devel zlib-devel c-ares-devel libressl-devel"
+depends="python3-six"
+short_desc="HTTP/2-based gRPC framework for Python"
+maintainer="Andrew J. Hesford <ajh@sideband.org>"
+license="Apache-2.0"
+homepage="https://grpc.io"
+distfiles="${PYPI_SITE}/g/grpcio/grpcio-${version}.tar.gz"
+checksum=01d3046fe980be25796d368f8fc5ff34b7cf5e1444f3789a017a7fe794465639
+
+if [ "$XBPS_TARGET_NO_ATOMIC8" ]; then
+	makedepends+=" libatomic-devel"
+fi
+
+if [ "$XBPS_TARGET_LIBC" = "musl" ]; then
+	makedepends+=" libexecinfo-devel"
+fi
+
+export GRPC_PYTHON_BUILD_SYSTEM_ZLIB=1
+export GRPC_PYTHON_BUILD_SYSTEM_CARES=1
+
+post_patch() {
+	if [ "${CROSS_BUILD}" ]; then
+		vsed -i setup.py -e "s@['\"]cc['\"]@'${CC}'@g" \
+			-e "/os.path.join/s@/usr@${XBPS_CROSS_BASE}/usr@g"
+		vsed -e "s@['\"]cc['\"]@'${CC}'@g" \
+			-i src/python/grpcio/commands.py
+	fi
+
+	# Use BoringSSL ASM when possible
+	local asm_key
+	case "${XBPS_TARGET_MACHINE}" in
+		x86_64*) asm_key=crypto_linux_x86_64;;
+		i686*) asm_key=crypto_linux_x86;;
+		aarch64*) asm_key=crypto_linux_aarch64;;
+		armv6l*|armv7l*) asm_key=crypto_linux_arm;;
+		ppc64le*) asm_key=crypto_linux_ppc64le;;
+		*) ;;
+	esac
+
+	vsed -i setup.py \
+		-e "s/asm_key = .*/asm_key = '${asm_key}'/" \
+		-e "s/if BUILD_WITH_BORING_SSL_ASM:/if False:/"
+}
diff --git a/srcpkgs/python3-grpcio/update b/srcpkgs/python3-grpcio/update
new file mode 100644
index 0000000000..864db4921b
--- /dev/null
+++ b/srcpkgs/python3-grpcio/update
@@ -0,0 +1 @@
+pattern="grpcio-\K[0-9.]+(?=.tar)"